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11 to 20 of 34 Results

Figure-1D. - Body Data.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 11.5 KB - 21 Variables, 56 Observations - UNF:6:Fve+Kk96uIpGR49ELjItqQ== Body area of stage-matched animals (at late L4 stage), relative to the median body area of their respective controls were plotted. Differences in the mean relative body area of each mutant, compared to its respective control, were quantified using ImageJ and statistical significa...
Figure-1E. Brood Size Assay Total.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 2.8 KB - 25 Variables, 14 Observations - UNF:6:mFIFbdviFfXSdzb4ATlkAw== Brood size of each haploinsufficient RP mutant, normalized to their respective wild-type controls, were plotted. Each dot represents an individual animal. Differences in the mean normalized brood size of each mutant, compared to its respective control, were analyzed using an inde...
Figure-2C_Left panel. Paraquat Survival Assay on RP Het Animals.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 704 B - 10 Variables, 13 Observations - UNF:6:laE792iyWYMWZMTFrSCzCQ== An acute time course of oxidative stress survival was plotted for large subunit RP mutants (first plot, rpl-5(0)/+ and rpl-33(0)/+) and small subunit RP mutants (second plot, rps-23(0)/+ and rps-10(0)/+), alongside wildtype control strains and daf-2(e13270) mutants serving as pos...
Figure-2C_right panel. Oxidative Survival Assay on RPL5 SKN-1 DAF-16 double mutant.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 692 B - 9 Variables, 13 Observations - UNF:6:hPr06eoeEhaJsJJ5nr/CaQ== An acute time course of oxidative stress survival was plotted for large subunit RP mutants (first plot, rpl-5(0)/+ and rpl-33(0)/+) and small subunit RP mutants (second plot, rps-23(0)/+ and rps-10(0)/+), alongside wildtype control strains and daf-2(e13270) mutants serving as pos...
Figure-4C merged_mitochondria_features.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 63.7 MB - 205 Variables, 67763 Observations - UNF:6:2BDTPiVStoVivaiKyfyIYQ== Quantification of the morphology of each individual mitochondria across all mutants and control animals, measured by convexity (degree to which shape differs from its convex hull), defect area (area outside of convex hull), and skeleton branch length. The density distribution of...
Figure-4C-mitochondria_sample_sizes.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 127 B - 2 Variables, 5 Observations - UNF:6:1rytHDh0RVNqa37JfRjHQA== Quantification of the morphology of each individual mitochondria across all mutants and control animals, measured by convexity (degree to which shape differs from its convex hull), defect area (area outside of convex hull), and skeleton branch length. The density distribution of...
Figure-5A. Mitotracker C elegans RP hetereozygous mutants.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 11.3 KB - 8 Variables, 101 Observations - UNF:6:Myww1iDxFGVwABQOIOwHRg== Mitochondrial activity, quantified via the uptake of fluorescent MitoTracker Red CMXRos Dye in each RP mutant compared to its wild-type counterpart, was plotted.
Figure-5B. ADP ATP ratio.xls May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration MS Excel Spreadsheet - 82.0 KB - MD5: 7f8a62d8679e5f4bab67b7d2041ac732 The ADP/ATP ratio, reflecting overall energy levels normalized to stage-matched controls, was presented for each mutant. Measurements from approximately 50 RP mutant and wild-type animals per biological replicate were used, with each replicate represented as a single dot on the...
Figure-5C. Oxygen consumption rps-10 and rps-23 heterozygous mutants.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 631 B - 3 Variables, 19 Observations - UNF:6:BrnqkHAvLeRxh4Dbcjpqqg== The average oxygen consumption of rps-23(0)/+ and rps-10(0)/+ mutants compared to wild type was plotted. Animals were carefully stage-matched to ensure similar body sizes, and oxygen consumption rates were normalized to the number of animals utilized in each assay
Figure-5E. rps-10 het mutant mitotracker rescue.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 11.1 KB - 7 Variables, 97 Observations - UNF:6:o0TrOGF6Ko8yYC/Qr21lRA== The normalized MitoTracker intensitywere evaluated in wild type and two [rps-10(0) to wildtype] rescued strains (rescue-1, rescue-2).

Figure-1D. - Body Data.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 11.5 KB - 21 Variables, 56 Observations -

Body area of stage-matched animals (at late L4 stage), relative to the median body area of their respective controls were plotted. Differences in the mean relative body area of each mutant, compared to its respective control, were quantified using ImageJ and statistical significa...

Figure-1E. Brood Size Assay Total.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 2.8 KB - 25 Variables, 14 Observations -

Brood size of each haploinsufficient RP mutant, normalized to their respective wild-type controls, were plotted. Each dot represents an individual animal. Differences in the mean normalized brood size of each mutant, compared to its respective control, were analyzed using an inde...

Figure-2C_Left panel. Paraquat Survival Assay on RP Het Animals.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 704 B - 10 Variables, 13 Observations -

An acute time course of oxidative stress survival was plotted for large subunit RP mutants (first plot, rpl-5(0)/+ and rpl-33(0)/+) and small subunit RP mutants (second plot, rps-23(0)/+ and rps-10(0)/+), alongside wildtype control strains and daf-2(e13270) mutants serving as pos...

Figure-2C_right panel. Oxidative Survival Assay on RPL5 SKN-1 DAF-16 double mutant.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 692 B - 9 Variables, 13 Observations -

Figure-4C merged_mitochondria_features.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 63.7 MB - 205 Variables, 67763 Observations -

Quantification of the morphology of each individual mitochondria across all mutants and control animals, measured by convexity (degree to which shape differs from its convex hull), defect area (area outside of convex hull), and skeleton branch length. The density distribution of...

Figure-4C-mitochondria_sample_sizes.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 127 B - 2 Variables, 5 Observations -

Figure-5A. Mitotracker C elegans RP hetereozygous mutants.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 11.3 KB - 8 Variables, 101 Observations -

Mitochondrial activity, quantified via the uptake of fluorescent MitoTracker Red CMXRos Dye in each RP mutant compared to its wild-type counterpart, was plotted.

Figure-5B. ADP ATP ratio.xls

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

MS Excel Spreadsheet - 82.0 KB -

The ADP/ATP ratio, reflecting overall energy levels normalized to stage-matched controls, was presented for each mutant. Measurements from approximately 50 RP mutant and wild-type animals per biological replicate were used, with each replicate represented as a single dot on the...

Figure-5C. Oxygen consumption rps-10 and rps-23 heterozygous mutants.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 631 B - 3 Variables, 19 Observations -

The average oxygen consumption of rps-23(0)/+ and rps-10(0)/+ mutants compared to wild type was plotted. Animals were carefully stage-matched to ensure similar body sizes, and oxygen consumption rates were normalized to the number of animals utilized in each assay

Figure-5E. rps-10 het mutant mitotracker rescue.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 11.1 KB - 7 Variables, 97 Observations -

The normalized MitoTracker intensitywere evaluated in wild type and two [rps-10(0) to wildtype] rescued strains (rescue-1, rescue-2).

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