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21 to 30 of 35 Results

Figure-5E. rps-10 het mutant mitotracker rescue.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 11.1 KB - 7 Variables, 97 Observations - UNF:6:o0TrOGF6Ko8yYC/Qr21lRA== The normalized MitoTracker intensitywere evaluated in wild type and two [rps-10(0) to wildtype] rescued strains (rescue-1, rescue-2).
Figure-5F. Oxygen consumption rps-10 mutation rescue lineages.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 693 B - 3 Variables, 18 Observations - UNF:6:eDC3woCGPIYnEC36wYrXlw== normalized oxygen consumption were evaluated in wild type and two [rps-10(0) to wildtype] rescued strains (rescue-1, rescue-2). (
Figure-5G. Cox-4-GFP Tomm-20-TagRFP rps-10 heretozygous mutant quantification.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 2.7 KB - 5 Variables, 34 Observations - UNF:6:TRJAj9U/jt8PjgdPiwToYg== The relative intensity of TOMM-20::TagRFP and COX-4::GFP levels in rps-10 (0)/+ mutants were quantified and plotted against stage-matched wild-type controls
Figure-5H_left. gcn-1 RNAi and gcn-1 mutant oxygen consumption.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 661 B - 3 Variables, 15 Observations - UNF:6:GXw+b6yILvpJjMV5MGeXVQ== Normalized oxygen consumption rates were plotted for gcn-1(n4827) mutants and gcn-1 RNAi compared to their controls (wild type and non-target RNAi) (left). The effects of rps-10 and rps-23 RNAi in a wild-type background (middle), alongside the rps-10 and gas-1 RNAi effects in gcn...
Figure-5H_middle. rps-10 and rps-23 RNAi Oxygen consumption.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 594 B - 3 Variables, 15 Observations - UNF:6:dVhy61mTHgrCUtZPQQXcsA== Normalized oxygen consumption rates were plotted for gcn-1(n4827) mutants and gcn-1 RNAi compared to their controls (wild type and non-target RNAi) (left). The effects of rps-10 and rps-23 RNAi in a wild-type background (middle), alongside the rps-10 and gas-1 RNAi effects in gcn...
Figure-5H_right. rps-10 and gas-1 RNAi on gcn-1 mutant background oxygen consumption.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 627 B - 3 Variables, 15 Observations - UNF:6:ELcudnuTHSOv+bKXf94IDw== Normalized oxygen consumption rates were plotted for gcn-1(n4827) mutants and gcn-1 RNAi compared to their controls (wild type and non-target RNAi) (left). The effects of rps-10 and rps-23 RNAi in a wild-type background (middle), alongside the rps-10 and gas-1 RNAi effects in gcn...
Figure-7B. RP mitotracker K562 knockdown.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 7.6 KB - 5 Variables, 105 Observations - UNF:6:bXQsTXwRAgUMvtPJFAQqaA== Normalized MitoTracker intensities in response to approximately 50% reduction of RPS10, RPL35A, RPL5, and RPS23 transcripts were plotted in comparison to nontarget siRNA, where mitotracker intensity was quantified for at least 100 cells in three biological replicates, and RNA lev...
Figure-7C. K562 RNAi with RP ADP-ATP.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 6.1 KB - 14 Variables, 90 Observations - UNF:6:qc6UeGy58rJHTSpkbsnBsQ== ADP/ATP ratios in response to approximately 50% knockdown of RPS10, RPL35A, RPL5, and RPS23 transcripts were plotted in comparison to non-target siRNA.
Figure-S1C Lifespan Assay Total.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 6.9 KB - 20 Variables, 55 Observations - UNF:6:Ut4Ns9IcLuHVy6BxiJVVkw== ) The lifespan of small subunit RP mutants (top) and large subunit mutants (bottom) were plotted along with their respective controls in the presence of FuDR (5-fluorodeoxyuridine). The Y-axis represents percent survival and “n” represents the total number of animals.
Figure-S2A and S2B. Survival on drug treatment with Paraquat.tab May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration Tabular Data - 1.1 KB - 5 Variables, 36 Observations - UNF:6:rkBOf7va/pBAvDsSIYZbzA== (A) Survival fractions were analyzed within 8 hours of oxidative stress after pretreatment of rapamycin, bortezomib, and cycloheximide in wild-type animals and rpl-5(0)/+ mutants. (B) Wild-type animals were pretreated with double combinations of rapamycin, bortezomib, and cyclohe...

Figure-5E. rps-10 het mutant mitotracker rescue.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 11.1 KB - 7 Variables, 97 Observations -

The normalized MitoTracker intensitywere evaluated in wild type and two [rps-10(0) to wildtype] rescued strains (rescue-1, rescue-2).

Figure-5F. Oxygen consumption rps-10 mutation rescue lineages.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 693 B - 3 Variables, 18 Observations -

normalized oxygen consumption were evaluated in wild type and two [rps-10(0) to wildtype] rescued strains (rescue-1, rescue-2). (

Figure-5G. Cox-4-GFP Tomm-20-TagRFP rps-10 heretozygous mutant quantification.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 2.7 KB - 5 Variables, 34 Observations -

The relative intensity of TOMM-20::TagRFP and COX-4::GFP levels in rps-10 (0)/+ mutants were quantified and plotted against stage-matched wild-type controls

Figure-5H_left. gcn-1 RNAi and gcn-1 mutant oxygen consumption.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 661 B - 3 Variables, 15 Observations -

Normalized oxygen consumption rates were plotted for gcn-1(n4827) mutants and gcn-1 RNAi compared to their controls (wild type and non-target RNAi) (left). The effects of rps-10 and rps-23 RNAi in a wild-type background (middle), alongside the rps-10 and gas-1 RNAi effects in gcn...

Figure-5H_middle. rps-10 and rps-23 RNAi Oxygen consumption.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 594 B - 3 Variables, 15 Observations -

Figure-5H_right. rps-10 and gas-1 RNAi on gcn-1 mutant background oxygen consumption.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 627 B - 3 Variables, 15 Observations -

Figure-7B. RP mitotracker K562 knockdown.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 7.6 KB - 5 Variables, 105 Observations -

Normalized MitoTracker intensities in response to approximately 50% reduction of RPS10, RPL35A, RPL5, and RPS23 transcripts were plotted in comparison to nontarget siRNA, where mitotracker intensity was quantified for at least 100 cells in three biological replicates, and RNA lev...

Figure-7C. K562 RNAi with RP ADP-ATP.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 6.1 KB - 14 Variables, 90 Observations -

ADP/ATP ratios in response to approximately 50% knockdown of RPS10, RPL35A, RPL5, and RPS23 transcripts were plotted in comparison to non-target siRNA.

Figure-S1C Lifespan Assay Total.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 6.9 KB - 20 Variables, 55 Observations -

) The lifespan of small subunit RP mutants (top) and large subunit mutants (bottom) were plotted along with their respective controls in the presence of FuDR (5-fluorodeoxyuridine). The Y-axis represents percent survival and “n” represents the total number of animals.

Figure-S2A and S2B. Survival on drug treatment with Paraquat.tab

May 6, 2024 - Cytosolic Ribosomal Protein Haploinsufficiency affects Mitochondrial Morphology and Respiration

Tabular Data - 1.1 KB - 5 Variables, 36 Observations -

(A) Survival fractions were analyzed within 8 hours of oxidative stress after pretreatment of rapamycin, bortezomib, and cycloheximide in wild-type animals and rpl-5(0)/+ mutants. (B) Wild-type animals were pretreated with double combinations of rapamycin, bortezomib, and cyclohe...

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